Sono-activatable engineered bacteria for antitumor therapy.

Wang, Yuanyuan; Yan, Fei · Cell Rep Med · 2024

editorial · Level V

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Abstract

Bacteria show promising potential in tumor treatment, but safety concerns limit their application. In this issue, Gao et al.<sup>1</sup> develop ultrasound-controlled engineered bacteria through integrating sono-activatable gene circuits, achieving local production and release of therapeutic cargos in tumor.

Medical subject headings