Controlled oxygen delivery to power tissue regeneration.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 38778053.
- Also identified by DOI 10.1038/s41467-024-48719-x and PMC identifier 11111456.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Oxygen plays a crucial role in human embryogenesis, homeostasis, and tissue regeneration. Emerging engineered regenerative solutions call for novel oxygen delivery systems. To become a reality, these systems must consider physiological processes, oxygen release mechanisms and the target application. In this review, we explore the biological relevance of oxygen at both a cellular and tissue level, and the importance of its controlled delivery via engineered biomaterials and devices. Recent advances and upcoming trends in the field are also discussed with a focus on tissue-engineered constructs that could meet metabolic demands to facilitate regeneration.
Medical subject headings
- Oxygen
- Tissue Engineering
- Regeneration