Assessment of gaze direction during head and neck irradiation and dosimetric impact on the retina, macula and papilla in a cohort of 240 patients with paraoptic tumors.

Azemar, Nathan; Fontbonne, Cathy; Claude Quintyn, Jean; Lebertz, Dorothee; Marc Fontbonne, Jean; Thariat, Juliette · Radiother Oncol · 2024

prospective_cohort · Level II

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Abstract

In a prospective cohort of 240 paraoptic tumors patients treated with protons, there was 10° inter-individual gaze angle variability (up to 30°). In a random 21-patient subset with initial CTs versus and adaptive CTs, 6 (28.57 %) patients had at least twice a 10°-difference in their gaze angle, with > 5 Gy difference on the retina/macula or papilla in 2/21 (9.52 %) and 1/21 (4.76 %) based on cumulative dose from rescans, respectively.

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