A microbial-derived succinylated bile acid to safeguard liver health.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 38788691.
- Also identified by DOI 10.1016/j.cell.2024.04.020.
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Abstract
In this issue of Cell, Nie and co-authors report that the microbe-derived bile acid (BA) 3-succinylated cholic acid protects against the progression of metabolic dysfunction-associated liver disease. Intriguingly, its protective mechanism does not involve traditional BA signaling pathways but is instead linked to the proliferation of the commensal microbe Akkermansia muciniphila.
Medical subject headings
- Akkermansia
- Bile Acids and Salts
- Periodicals as Topic