First Experience of Radionuclide Therapy With 177Lu-FAPI-2286 in a Patient With Metastatic Mediastinal Sarcoma.

Banihashemian, Seyedeh Somayyeh; Bayat, Mohadese; Pirayesh, Elahe; Divband, Ghasemali; Abolhosseini, Abdolghafar; Akbari, Mohammad Esmaeel · Clin Nucl Med · 2024

case_report · Level V

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Abstract

Fibroblast activation protein (FAP) is a new promising molecular target for theragnostic approach. FAP inhibitors (FAPIs) labeled with 177Lu could be potentially a therapeutic radiopharmaceutical. Here, we presented the experience of 4 cycles of 177Lu-FAPI in a 67-year-old man with an unresectable mediastinal sarcoma.

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