On mechanical phase and form.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 38848672.
- Also identified by DOI 10.1016/j.cell.2024.04.045.
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Abstract
Epithelial folding is a fundamental biological process that requires epithelial interactions with the underlying mesenchyme. In this issue of Cell, Huycke et al. investigate intestinal villus formation. They discover that water-droplet-like behavior of mesenchymal cells drives their coalescence into uniformly patterned aggregates, which generate forces on the epithelium to initiate folding.
Medical subject headings
- Mesoderm
- Epithelium