Redefining intestinal stemness: The emergence of a new ISC population.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 38848673.
- Also identified by DOI 10.1016/j.cell.2024.04.021.
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Abstract
In tissue homeostasis, intestinal stem cells (ISCs) undergo continuous self-renewal to sustain rapid cellular turnover. In this issue of Cell, Capdevila et al.<sup>1</sup> and Malagola, Vasciaveo, et al.<sup>2</sup> identify a new ISC population in the upper crypt that can generate Lgr5<sup>+</sup> stem cells during homeostasis.
Medical subject headings
- Stem Cells
- Intestines