CAR macrophages tuning the immune symphony of anti-cancer therapies.
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 38848684.
- Also identified by DOI 10.1016/j.stem.2024.05.006.
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Abstract
Chimeric antigen receptor (CAR) macrophages have broadened the landscape of anti-cancer immunotherapies to combat solid malignancies. Shah et al. introduce CARs to facilitate a CAR macrophage therapy, which aims to recruit and activate T/natural killer cells, further strengthening the overall immune response to decrease pancreatic cancer burden and metastatic spreading.
Medical subject headings
- Macrophages
- Receptors, Chimeric Antigen