Greasing the machinery toward maturation of stem cell-derived β cells.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 38848685.
- Also identified by DOI 10.1016/j.stem.2024.05.001.
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Abstract
Getting mature and functional stem cell-derived, insulin-producing β cells is an important step for disease modeling, drug screening, and cell replacement therapy. In this issue, Hua et al.<sup>1</sup> used single-cell multiomics analysis coupled with chemical screening to identify a crucial role for ceramides in generating mature stem cell-derived β cells.
Medical subject headings
- Insulin-Secreting Cells
- Cell Differentiation