Triggers for eosinophilic esophagitis (EoE): The intersection of food allergy and EoE.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 38849185.
- Also identified by DOI 10.1016/j.jaci.2024.04.010 and PMC identifier 11414349.
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Abstract
Eosinophilic esophagitis and IgE-mediated food allergy are both food-triggered diseases that are increasing in prevalence. They share many clinical links, including significant comorbidity and similar food triggers, and as atopic diseases, they likely share upstream mechanisms related to barrier function and signals leading to T<sub>H</sub>2 skewing. In this review, we focus on links between eosinophilic esophagitis and IgE-mediated food allergy with an emphasis on what insights may be derived from overlapping food triggers and immune phenotypes. Through further investigation of these connections, we may be able to better understand not only IgE-mediated food allergy and eosinophilic esophagitis but also general atopic response to food proteins and evolution of allergic response to food.
Medical subject headings
- Eosinophilic Esophagitis
- Food Hypersensitivity