The dynamic world of the 8-17 DNAzyme.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 38886339.
- Also identified by DOI 10.1038/s41467-024-49500-w and PMC identifier 11183194.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
DNA catalysts, known as DNAzymes, have arguably been limited for decades by the lack of mechanistic information. The solution structure of the 8–17 DNAzyme reported by Wieruszekska, Pwlowicz et al. reassesses the current thinking regarding the relationship between structure, dynamic, and metal ion coordination.
Medical subject headings
- DNA, Catalytic