BAllC and BAllCools: efficient formatting and operating for single-cell DNA methylation data.
Where this comes from
- Record sourced from PubMed, PMID 38905499.
- Also identified by DOI 10.1093/bioinformatics/btae404 and PMC identifier 11216754.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
With single-cell DNA methylation studies yielding vast datasets, existing data formats struggle with the unique challenges of storage and efficient operations, highlighting a need for improved solutions. BAllC (Binary All Cytosines) emerges as a tailored format for methylation data, addressing these challenges. BAllCools, its complementary software toolkit, enhances parsing, indexing, and querying capabilities, promising superior operational speeds and reduced storage needs. https://github.com/jksr/ballcools.
Medical subject headings
- DNA Methylation
- Single-Cell Analysis
- Software