False-Positive Bone Lesion With Different PET/CT Tracers: Beyond Thrombosis, Be Aware of Any Collateral Circulation.

Moreau, Aurélie; Pretet, Valentin; Kryza, David · Clin Nucl Med · 2024

case_report · Level V

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Abstract

Collateral circulation is often secondary to a regional thrombosis. This phenomenon can lead to the detection of misleading bone lesions on imaging and is a well-known source of false-positives. Here, we present 2 different tracers PET/CT images, 18 F-FDG and 18 F-choline, with collateral circulation but without obvious thrombosis. Both cases displayed bone uptake, which mimicked metastasis. However, clinical follow-up ruled out metastasis and revealed false-positive bone lesions related to collateral circulation, even in the lack of acute or chronic underlying thrombotic processes.

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