SGLT-2 inhibitors in heart failure and chronic kidney disease: A review for internists.

Jaswaney, Rahul; Sokoloff, Samantha; Rakita, Val; Rubin, Daniel J · Cleve Clin J Med · 2024

review · Level V

Where this comes from

Abstract

Despite current therapies, heart failure and chronic kidney disease continue to be major causes of morbidity and mortality. Sodium-glucose cotransporter 2 (SGLT-2) inhibitors have recently become standard-of-care therapy for these conditions. This review summarizes important randomized controlled trials of SGLT-2 inhibitors and guidelines for using these agents in patients with heart failure and chronic kidney disease in both clinic and hospital settings.

Medical subject headings