Rapid Wane and Recovery of XBB Sublineage Neutralization After Sequential Omicron-based Vaccination in Solid Organ Transplant Recipients.
prospective_cohort · Level II
Where this comes from
- Record sourced from PubMed, PMID 38953683.
- Also identified by DOI 10.1093/cid/ciae279 and PMC identifier 11426267.
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Abstract
Durability of variant neutralization in solid organ transplant recipients following Omicron-containing boosters is unknown. We report wane in XBB.1.5 neutralization by 3 months following a first bivalent booster, improved by a second booster; hybrid immunity improved peak, and duration of neutralization. Boosting at 3 to 6 months appears necessary to maintain neutralization.
Medical subject headings
- Transplant Recipients
- SARS-CoV-2
- COVID-19
- Antibodies, Neutralizing
- Immunization, Secondary
- Organ Transplantation
- Antibodies, Viral
- COVID-19 Vaccines