From whence it came: Mitochondrial mRNA leaves, a protein returns.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 38959859.
- Also identified by DOI 10.1016/j.cmet.2024.06.002.
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Abstract
Small peptides have previously been reported to be encoded in mitochondrial rRNA and translated by cytosolic ribosomes. In this issue of Cell Metabolism, Hu et al. use mass spectrometry to identify a cytosolically translated protein, encoded instead in mitochondrial mRNA, that is surprisingly targeted back into the mitochondrial matrix.
Medical subject headings
- RNA, Messenger
- Mitochondria