Fit for purpose: Selecting the best mitochondrial DNA for the job.
Where this comes from
- Record sourced from PubMed, PMID 38959860.
- Also identified by DOI 10.1016/j.cmet.2024.06.011.
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Abstract
The factors determining levels of pathogenic mitochondrial DNA in cells and tissues are critical to disease pathology but remain poorly understood and contentious. In Nature, Kotrys et al. published a single-cell-based analysis casting fresh light on this thorny problem and introduced a powerful new investigative tool.
Medical subject headings
- DNA, Mitochondrial