Imaging of Hypoxia in Liver Tumors With 18 F-FMISO PET Before Selective Internal Radiotherapy With 90 Y Microspheres.

Soydal, Cigdem; Demir, Burak; Dursun, Ecenur; Sutcu, Gizem; Celebioglu, Emre Can; Bilgic, Mehmet Sadik; Kucuk, Nuriye Ozlem · Clin Nucl Med · 2024

case_report · Level V

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Abstract

Hypoxia is a known cause of resistance to radiotherapy and chemotherapy. Although there are multiple studies in external radiation therapies based on hypoxia PET, the effect of hypoxia in radioembolization is largely unknown. Here we present 2 cases of hepatocellular carcinoma patients from a prospective study with different lesion characteristics on pretreatment 18 F-FMISO PET and varying responses on 18 F-FDG PET.

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