Monkey see, monkey do: Tracking iPS-cardiomyocyte survival and maturation in autografts.

Ji, Xiaoqian; Wang, Qiyuan; Cao, Nan · Cell Stem Cell · 2024

basic_science · Level V

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Abstract

Induced pluripotent stem cell-derived cardiomyocyte (iPSC-CM) therapy has emerged as a highly promising field of heart repair. Lin et al.<sup>1</sup> presented compelling evidence on the long-term engraftment and maturation of autologous iPSC-CMs in two rhesus macaques, demonstrating unprecedented cardiac autografting data in large animal models without the need of immunosuppressants.

Medical subject headings