Oscillation steers differentiation.

LaBella, Kyle A; Reyes, Efren A; Vermeulen, Louis · Cell Stem Cell · 2024

editorial · Level V

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Abstract

The differentiation trajectories defining enteroendocrine (EE) cell heterogeneity remain obscure. In this issue of Cell Stem Cell, Singh et al.<sup>1</sup> map the differentiation landscape of EE cells, identifying early oscillating cell progenitor states, which play a critical role in generating terminal EE cell diversity.

Medical subject headings