Unraveling the function of FGF signaling in human hypoblast specialization.

Wu, Hao; Zhai, Jinglei; Wang, Hongmei · Cell Stem Cell · 2024

basic_science · Level V

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Abstract

Dattani et al.<sup>1</sup> developed a method for inducing hypoblast-like cells from human naive pluripotent stem cells. They elucidated the requirement for FGF signaling in human hypoblast specialization at a specific time window, which was previously controversial.

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