Polyethylene Glycol-Fusion Repair of Peripheral Nerve Injuries.

Bittner, George D; Tuffaha, Sami; Shores, Jaimie T · Hand Clin · 2024

review · Level V

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Abstract

Axons successfully repaired with polyethylene glycol (PEG) fusion tecnology restored axonal continuity thereby preventing their Wallerian degeneration and minimizing muscle atrophy. PEG fusion studies in animal models and preliminary clinical trials involving patients with digital nerve repair have shown promise for this therapeutic approach. PEG fusion is safe to perform, and given the enormous potential benefits, there is no reason not to explore its therapeutic potential.

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