Cartilage compositional MRI-a narrative review of technical development and clinical applications over the past three decades.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 38980364.
- Also identified by DOI 10.1007/s00256-024-04734-z and PMC identifier 11303573.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
Articular cartilage damage and degeneration are among hallmark manifestations of joint injuries and arthritis, classically osteoarthritis. Cartilage compositional MRI (Cart-C MRI), a quantitative technique, which aims to detect early-stage cartilage matrix changes that precede macroscopic alterations, began development in the 1990s. However, despite the significant advancements over the past three decades, Cart-C MRI remains predominantly a research tool, hindered by various technical and clinical hurdles. This paper will review the technical evolution of Cart-C MRI, delve into its clinical applications, and conclude by identifying the existing gaps and challenges that need to be addressed to enable even broader clinical application of Cart-C MRI.
Medical subject headings
- Humans
- Cartilage, Articular
- Cartilage, Articular/diagnostic imaging
- Magnetic Resonance Imaging
- Magnetic Resonance Imaging/methods
- Osteoarthritis
- Osteoarthritis/diagnostic imaging