Patient-derived tumor organoids to model drug response in gastric cancer.

Vistoso Monreal, Anette; Zhao, Hua; Sedghizadeh, Parish P; Lin, De-Chen · Cell Rep Med · 2024

basic_science · Level V

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Abstract

Gastric cancer poses diverse treatment challenges due to its high tumor heterogeneity. Through the use of patient-derived tumor organoid (PDO) models, new research<sup>1</sup> has identified genes and molecular signatures that are predictive of chemotherapeutic response, providing valuable insights for clinical management and translational advancements.

Medical subject headings