The Fragility Index: Understanding Its Application in Clinical Research.

Meade, Matthew H; Buchan, Levi; Michael, Mark; Woods, Barrett · Clin Spine Surg · 2024

review · Level V

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Abstract

With the vast increase in spinal surgery research and accessibility, critical evaluation of studies is paramount. Historically, P values and confidence intervals have been the gold standard, but more recently, the inclusion of the Fragility Index has brought a more holistic approach. The Fragility Index aims to communicate the robustness of a trial and how tenuous statistical significance may be. It can be used in conjunction with more traditional methods for evaluating research.

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