Effect of Vaginal Microecological Disorders on the Increased Risk of Abnormal Cervical Cytology Among Women With Human Immunodeficiency Virus in China.

Wang, Xiaolei; Zhang, Yuanyuan; Xiao, Jiang; Song, Chuan; Liu, Tingting; Liu, Jun; Zhao, Hongxin · J Infect Dis · 2024

cross_sectional · Level IV

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Abstract

Abnormal cervical cytology is commonly observed in women with human immunodeficiency virus (WWH). A cross-sectional study was conducted with 130 WWH and 147 age-matched healthy controls, who underwent gynecological examinations at Beijing Ditan Hospital. The presence of abnormal cervical cytology in WWH was predicted after performing a logistic regression analysis. Multivariate logistic regression revealed 3 independent factors, among which CD4 cell count ≥350 cells/μL was the protective factor, while human papillomavirus infection and abnormal vaginal pH were the risk factors. Vaginal microecological disorders can increase the risk of abnormal cervical cytology in WWH.

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