A False-Negative 123 I-MIBG SPECT/CT With True-Positive 68 Ga-DOTATATE PET/CT in a Patient With Neuroblastoma Following 177 Lu-DOTATATE Therapy.
case_report · Level V
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- Record sourced from PubMed, PMID 39093037.
- Also identified by DOI 10.1097/RLU.0000000000005397.
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Abstract
A 10-year-old girl with high-risk neuroblastoma underwent 123 I-MIBG SPECT/CT and 68 Ga-DOTATE PET/CT, which both showed multiple bone metastases. However, following 177 Lu-DOTATATE therapy, only 68 Ga-DOTATATE PET/CT identified residual lesions with negative 123 I-MIBG SPECT/CT results. The case emphasized the complementary role of 68 Ga-DOTATATE PET/CT and 123 I-MIBG SPECT/CT after 177 Lu-DOTATATE therapy.
Medical subject headings
- Neuroblastoma
- Organometallic Compounds
- 3-Iodobenzylguanidine
- Positron Emission Tomography Computed Tomography
- Octreotide
- Single Photon Emission Computed Tomography Computed Tomography