Mini-colons predict drug toxicity in vitro.

Mora-Boza, Ana; García, Andrés J · Cell Stem Cell · 2024

basic_science · Level V

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Abstract

Mitrofanova et al.<sup>1</sup> engineer a human colonic in vitro model capable of producing an intestinal mucus barrier, with potential applications for predicting drug-induced gastrointestinal toxicity. This improved system paves the way for more accurate and efficient drug development processes.

Medical subject headings