Engineered vascular grafts lend unique insight to pathophysiology of aortic aneurysms.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 39094540.
- Also identified by DOI 10.1016/j.stem.2024.07.002.
- No licence information is recorded for this record.
- Because redistribution is not established, this page shows the abstract only. Follow the links below for the full text.
Abstract
Yang et al.<sup>1</sup> generate tissue engineered blood vessels from hiPSC-derived smooth muscle cells harboring a mutation found in Loeys-Dietz syndrome. In vitro and in vivo data from these vessels provide new insight into the molecular physiology of aortic aneurysms and may create a paradigm for understanding a suite of vascular diseases.
Medical subject headings
- Tissue Engineering
- Aortic Aneurysm
- Blood Vessel Prosthesis