Construction of homologous branched oligomer megamolecules based on linker-directed protein assembly.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 39177042.
- Also identified by DOI 10.1039/d4sm00673a.
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Abstract
Utilizing the building blocks of recombinant proteins and synthetic linkers, we have obtained two distinct octameric megamolecules with diverse branched structures. This approach combines principles from both click chemistry and protein engineering technology, enabling the integration of functional domains within highly ordered protein assemblies for biomedical applications.
Medical subject headings
- Protein Engineering