OLAH connects fatty acid metabolism to the severity of respiratory viral disease.

Palanki, Rohan; Yamagata, Hannah; Mitchell, Michael J · Cell · 2024

editorial · Level V

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Abstract

Respiratory virus infections may cause profound respiratory illness, yet the factors that underlie disease severity are not well understood. In this issue of Cell, Jia, Crawford, et al.<sup>1</sup> identify the role of oleoyl-ACP-hydrolase (OLAH) in mediating life-threatening inflammation associated with viral respiratory disease severity.

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