Vulvar Cancer: Histopathologic Considerations and Nuances to Management.

Burt, Lindsay; Jarboe, Elke; Gaffney, David; Suneja, Gita; DeCesaris, Cristina; Bedell, Sabrina; Brower, Jeffrey · Pract Radiat Oncol · 2025

review · Level V

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Abstract

Vulvar cancer, although rare, poses significant challenges in diagnosis and treatment because of its histopathologic complexities and nuances. This paper reviewed key aspects of the management of vulvar cancer, focusing on histopathologic diagnosis, margin status interpretation, lymph node involvement assessment, and ongoing clinical trials.

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