Humans are unreliable models of mouse disease.
expert_opinion · Level V
Where this comes from
- Record sourced from PubMed, PMID 39241741.
- Also identified by DOI 10.1016/j.cell.2024.08.006.
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Abstract
In defying conventional views that dismissed itch as trivial, I persisted in studying basophils and ILC2s in human skin and atopic dermatitis. My research on JAK inhibitors for itch ultimately led to FDA-approved drugs. This is my story of disregarding categories and definitions-a story about an unconventional path in science that emphasizes innovation over conformity.
Medical subject headings
- Disease Models, Animal
- Dermatitis, Atopic
- Pruritus