The Intrauterine Device: How to Deploy This Strategy in the Molecular World?

Johannet, Paul; Friedman, Claire F · Clin Cancer Res · 2024

editorial · Level V

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Abstract

Progestin-based therapy can safely be offered to a subset of patients with atypical endometrial hyperplasia or grade 1 endometrioid endometrial cancer who desire fertility preservation. A recent study shows that levonorgestrel intrauterine device confers durable clinical benefit and identifies possible immune mechanisms of relapse and resistance. See related article by Bowen et al., p. 5073.

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