Main-group compounds selectively activate natural gas alkanes under room temperature and atmospheric pressure.

Pei, Runbo; Chang, Wenju; He, Liancheng; Wang, Tao; Zhao, Yue; Liang, Yong; Wang, Xinping · Nat Commun · 2024

basic_science · Level V

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Abstract

Most C-H bond activations of natural gas alkanes rely on transition metal complexes. Activations by using main-group systems have been reported but required heating or photo-irradiation under high atmospheric pressure with rather low regioselectivity. Here we report that Lewis acid-carbene adducts facilely undergo oxidative additions to C-H bonds of ethane, propane and n-butane with high selectivity under room temperature and atmospheric pressure. The Lewis acids can be moved by the addition of a base and the carbene-derived products can be easily converted into aldehydes. This work offers a route for main-group element compounds to selectively functionalise C-H bonds of natural gas alkanes and other small molecules.