Lock out SIRT4.
Where this comes from
- Record sourced from PubMed, PMID 39269433.
- Also identified by DOI 10.7554/eLife.102355 and PMC identifier 11398859.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
The accumulation of SIRT4 in the nuclei of kidney cells drives kidney fibrosis, so blocking the movement of this protein could be a potential therapeutic strategy against fibrosis.
Medical subject headings
- Sirtuins
- Fibrosis