Decoding the diabetic bone paradox: How AGEs sabotage skeletal integrity.

Wang, Juan; Cui, Wenguo · Cell Rep Med · 2024

review · Level V

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Abstract

Diabetes patients often suffer from fractures despite normal or high bone mineral density, a phenomenon known as the diabetic bone paradox. Gao et al.<sup>1</sup> identify AGEs as disrupting bone quality and compromising skeletal integrity in diabetic bone disease.

Medical subject headings