Exploring RNA-guided DNA scissors in eukaryotes: Are Fanzors counterparts of CRISPR-Cas12s?
editorial · Level V
Where this comes from
- Record sourced from PubMed, PMID 39303688.
- Also identified by DOI 10.1016/j.cell.2024.08.022.
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Abstract
Fanzors are recently characterized RNA-guided DNA endonucleases found in eukaryotic organisms. In this issue of Cell, Xu, Saito et al. reveal the structural diversity of Fanzors and identify key features shared with TnpB and Cas12 proteins, providing a comprehensive perspective on their molecular function and evolution.
Medical subject headings
- CRISPR-Cas Systems