A prokaryotic Argonaute protein recruits a helicase-nuclease to degrade invading plasmids.
basic_science · Level V
Where this comes from
- Record sourced from PubMed, PMID 39303689.
- Also identified by DOI 10.1016/j.cell.2024.08.031.
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Abstract
DdmDE is a novel plasmid defense system that was discovered in the seventh pandemic Vibrio cholerae strain of the biotype O1 EI Tor. In this issue of Cell, Yang and coworkers reveal the mechanisms underlying the assembly and activation of the DdmDE defense system.
Medical subject headings
- Plasmids
- Vibrio cholerae