Cilastatin, a new therapeutic promise for acute kidney injury.
review · Level V
Where this comes from
- Record sourced from PubMed, PMID 39304269.
- Also identified by DOI 10.1016/j.kint.2024.07.024.
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Abstract
Acute kidney injury is a devasting clinical syndrome resulting from multiple causes, characterized by an abrupt deterioration of kidney function for which there is no pharmacologic treatment. Cilastatin has demonstrated direct nephroprotective effects in acute kidney injury and now is shown to be effective to specifically target therapeutically loaded nanoparticles to the proximal tubule to treat acute kidney injury.
Medical subject headings
- Acute Kidney Injury
- Cilastatin