The revolution in high-throughput proteomics and AI.
review · Level V
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- Record sourced from PubMed, PMID 39325883.
- Also identified by DOI 10.1126/science.ads5749.
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Abstract
The recent capability to measure thousands of plasma proteins from a tiny blood sample has provided a new dimension of expansive data that can advance our understanding of human health. For example, the company SomaLogic has developed the means to measure more than 10,000 proteins and Thermo Fisher's Olink assays over 5400 proteins from as little as 2 μl. When these rich data are integrated with other layers of information from large patient cohorts, such as the UK Biobank's genetic, health, and lifestyle information from half a million participants, we get new insights about the underpinnings of disease, the aging process, and the potential ability to forecast an individual's health trajectory.
Medical subject headings
- Artificial Intelligence
- Blood Proteins
- High-Throughput Screening Assays
- Proteomics