Health State Utility is Substantially Reduced With an Increasing Burden of Patient-Reported Symptoms in Eosinophilic Esophagitis.
cross_sectional · Level IV
Where this comes from
- Record sourced from PubMed, PMID 39329387.
- Also identified by DOI 10.14309/ajg.0000000000003106.
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Abstract
We aimed to estimate health state utility in eosinophilic esophagitis (EoE) by histologic activity and assess association with disease parameters. In this cross-sectional study, we measured health state utility by time trade-off and assessed symptoms with the EoE Symptom Activity Index. In 51 adults with EoE, the mean utility was 0.91 (95% CI 0.86, 0.95). Utility was numerically worse in patients with dilation or a smaller stricture diameter. With each ten-point improvement in EoE Symptom Activity Index, utility increased by 0.03 (95% CI 0.01, 0.05). EoE is associated with reduced health state utility, with symptoms most strongly predicting valuation.
Medical subject headings
- Eosinophilic Esophagitis
- Patient Reported Outcome Measures
- Quality of Life
- Health Status