Specifically Decreased Thalamic Blood Flow Following COVID-19 Infection.

Matsubayashi, Taiki; Yokoyama, Kota; Tateishi, Ukihide; Yokota, Takanori; Sanjo, Nobuo · Clin Nucl Med · 2024

case_report · Level V

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Abstract

Although long COVID refers to numerous COVID-19-related symptoms after infection, including depression, fatigue, anosmia, sleep disturbances, and brain fog, the etiology of long COVID remains largely unknown. A 41-year-old woman presented with a 3-week history of complete insomnia without drowsiness throughout the day after contracting COVID-19. SPECT using N -isopropyl-p-[ 123 I] iodoamphetamine showed a significant regional cerebral blood flow reduction in the bilateral thalamus. We diagnosed her as having insomnia accompanied by thalamic hypoperfusion related to COVID-19 infection. To our knowledge, this is the first case of reduced regional cerebral blood flow specifically confined to the thalamus.

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