Concurrent Intracranial and Spinal Dural Metastases Demonstrated by 68 Ga-DOTATATE PET/CT With Negative 123 I-MIBG SPECT/CT in a Pediatric Neuroblastoma Patient.
case_report · Level V
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- Record sourced from PubMed, PMID 39354700.
- Also identified by DOI 10.1097/RLU.0000000000005448.
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Abstract
Contrast enhancement MRI of the brain and spine showed abnormal enhancement in intracranial and spinal dural lesions in a 6-year-old boy with high-risk neuroblastoma, suggesting the possibility of dural metastases. 123 I-MIBG SPECT/CT did not show any abnormal MIBG accumulation in these lesions. However, 68 Ga-DOTATATE PET/CT showed obvious DOTATATE uptake in these metastatic lesions. Surgical pathology confirmed the diagnosis of intracranial dural metastasis. Concurrent intracranial and spinal dural metastases from neuroblastoma demonstrated by 68 Ga-DOTATATE PET/CT with negative 123 I-MIBG SPECT/CT have not been reported previously.
Medical subject headings
- Neuroblastoma
- Organometallic Compounds
- Positron Emission Tomography Computed Tomography
- Brain Neoplasms
- 3-Iodobenzylguanidine
- Single Photon Emission Computed Tomography Computed Tomography