Retrospective Data-Driven Motion Correction of 18 F-FDG Brain PET.
retrospective_cohort · Level III
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- Record sourced from PubMed, PMID 39365097.
- Also identified by DOI 10.1097/RLU.0000000000005443.
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Abstract
A 51-year-old man with severe multifactorial neurocognitive disorders subsequent to delirium, benzodiazepine withdrawal, and preexisting psychiatric illness was referred for 18 F-FDG PET/CT brain imaging in order to rule out an underlying neurodegenerative cause of the symptoms, particularly frontotemporal lobar degeneration. Imaging was impaired by severe motion artifacts, leading to a false-positive result. However, utilizing retrospective data-driven motion correction facilitated a change in diagnosis, ruling out the presence of neurodegenerative disease. The implementation of motion correction of the 18 F-FDG PET dataset proved crucial for the patient, as the exclusion of frontotemporal lobar degeneration formed the basis for continuing psychiatric and psychotherapeutic treatment.
Medical subject headings
- Fluorodeoxyglucose F18
- Brain
- Positron-Emission Tomography