Let's get functional: Drug sensitivity profiling to enable precision sarcoma medicine.

Ball, Claudia R; Fröhling, Stefan · Cell Stem Cell · 2024

editorial · Level V

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Abstract

Drug sensitivity profiling in patient-derived tumor models offers new hope for improving outcomes in cancers lacking effective therapies. Al Shihabi et al.<sup>1</sup> demonstrate that short-term cultures from bone and soft tissue sarcomas enable clinically meaningful screening of multiple drugs and combinations, marking a significant advance in personalized care for these high-risk diseases.

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