BioPred: an R package for biomarkers analysis in precision medicine.
other · Level V
Where this comes from
- Record sourced from PubMed, PMID 39374538.
- Also identified by DOI 10.1093/bioinformatics/btae592 and PMC identifier 11483108.
- Licence recorded as CC BY.
- The licence permits redistribution, so the abstract is shown in full and the full text is available from the publisher.
Abstract
The R package BioPred offers a suite of tools for subgroup and biomarker analysis in precision medicine. Leveraging Extreme Gradient Boosting (XGBoost) along with propensity score weighting and A-learning methods, BioPred facilitates the optimization of individualized treatment rules to streamline subgroup identification. BioPred also enables the identification of predictive biomarkers and obtaining their importance rankings. Moreover, the package provides graphical plots tailored for biomarker analysis. This tool enables clinical researchers seeking to enhance their understanding of biomarkers and patient population in drug development. The package is available at CRAN and https://github.com/deeplearner0731/BioPred.
Medical subject headings
- Precision Medicine
- Software
- Biomarkers