Risk Factors for Serrated Polyps: Results From a Large, Multicenter Colonoscopy-Based Study.
cross_sectional · Level IV
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- Record sourced from PubMed, PMID 39382983.
- Also identified by DOI 10.14309/ajg.0000000000003035 and PMC identifier 12217339.
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Abstract
Risk factors for serrated polyps (SPs) are not well understood. Multivariable analyses of data from a multicenter colonoscopy-based study estimated odds ratios for having either a sessile serrated lesion or traditional serrated adenoma according to participant characteristics. Six thousand seventy-eighty participants were included in the analyses (565 with either a sessile serrated lesion or traditional serrated adenoma). White race was associated with a higher risk of SPs compared with Black race (adjusted odds ratio 4.64, 95% confidence interval 1.89-11.41). Obesity and current smoking were also associated with a higher risk of SPs. White race, smoking, and obesity are risk factors for precancerous SPs.
Medical subject headings
- Adenoma
- Colonic Polyps
- Colonoscopy
- Obesity