Poly (ADP-ribose) Polymerase Inhibitor Resistance Driven by Emergence of Polyclonal Mutations With Convergent Evolution: A Molecular Tumor Board Discussion.
case_report · Level V
Where this comes from
- Record sourced from PubMed, PMID 39393037.
- Also identified by DOI 10.1200/PO.24.00254 and PMC identifier 11485209.
- Licence recorded as CC BY-NC-ND.
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Abstract
Polyclonal convergent evolution to PARPi resistance in a patient with metastatic breast cancer with gPALB2.
Medical subject headings
- Poly(ADP-ribose) Polymerase Inhibitors
- Drug Resistance, Neoplasm
- Mutation
- Breast Neoplasms