68 Ga-DOTATATE and 18 F-FDG PET/CT in a Rapidly Progressing Lymphoma.
case_report · Level V
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- Record sourced from PubMed, PMID 39397315.
- Also identified by DOI 10.1097/RLU.0000000000005450.
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Abstract
68 Ga-DOTATATE PET/CT targeting somatostatin receptors is commonly utilized in the imaging of neuroendocrine tumors. However, other malignancies such as lymphomas (both Hodgkin and non-Hodgkin) also have expression of somatostatin receptors, albeit to a lesser degree compared with the neuroendocrine tumors, and thus can be positive on a 68 Ga-DOTATATE PET/CT. We describe an atypical presentation of an aggressive large B-cell lymphoma mimicking a metastatic neuroendocrine tumor at initial presentation with high somatostatin receptor expression demonstrated on the 68 Ga-DOTATATE PET/CT and a rapidly progressing course on the subsequent 18 F-FDG PET/CT.
Medical subject headings
- Disease Progression
- Fluorodeoxyglucose F18
- Organometallic Compounds
- Positron Emission Tomography Computed Tomography